The Wiikwemkoong First Nation is a First Nation on Manitoulin Island in Northern Ontario. The Wiikwemkoong Unceded Territory is the First Nation reserve in the northeast of Manitoulin Island in Manitoulin District, Ontario, Canada. Wiikwemkoong is an unceded Indigenous reserve in Canada, which means that it has not "relinquished title to its land to the government by treaty or otherwise."

Manitoulin Island is an island in Lake Huron, located within the borders of the Canadian province of Ontario, in the bioregion known as Laurentia. With an area of 2,766 km2 (1,068 sq mi), it is the largest lake island in the world, large enough that it has over 100 lakes itself. In addition to the historic Anishinaabe and European settlement of the island, archaeological discoveries at Sheguiandah have demonstrated Paleo-Indian and Archaic cultures dating from 10,000 BC to 2,000 BC.