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William Allen (governor)

William Allen was a Democratic Representative, Senator and 31st Governor of Ohio. Allen was born in Edenton, North Carolina and moved to Chillicothe, Ohio in 1819, after his parents' death, he was of Quaker ancestry. Allen and his sister Mary Granberry Allen lived in Chillicothe together, his sister married Reverend Pleasant Thurman, their son, Allen G. Thurman, followed in his uncle's footsteps, becoming a lawyer and politician. Allen attended Chillicothe Academy before studying law with Colonel Edward King, he was admitted to the bar in Ohio at age 21. He began his career as a politician in the Democratic Party at a young age. Allen served as United States Representative from Ohio from 1833 to 1835, losing his bid for re-election, he served as United States Senator from Ohio from 1837 to 1849, losing a bid for a third term in 1848. While in the Senate, Allen was one of a group of Western Democrat expansionists who asserted that the U. S. had a valid claim to the entire Oregon Country, an issue during the 1844 U.

S. presidential election. He suggested that the United States should be prepared to go to war with the United Kingdom in order to annex the entire Oregon Country up to Russian-owned Alaska at latitude 54°40′N; this position produced the slogan "Fifty-Four Forty or Fight!," coined in 1846 by opponents of such a policy. Allen supported "popular sovereignty" and the presidential candidacy of fellow-Democrat Lewis Cass in 1848. In 1849, Allen retired to his farm, "Fruit Hill", which had belonged to his father-in-law, fellow Ohio Governor, Duncan McArthur, near Chillicothe, Ohio. Allen identified himself as a "Peace Democrat" by opposing the American Civil War. Allen did not return to public service for nearly a quarter century, until he served as Governor of Ohio from 1874 to 1876, he unsuccessfully sought a second two-year term in an 1875 election. Allen was noted for his loud voice. A friend asked Senator Benjamin Tappan. Tappan replied "No, he left yesterday and is by this time in Cumberland, but if you will go to Bill Allen and tell him to raise that window and call him he will come back."

At the close of his administration, he retired to private life at Fruit Hill, where he died in 1879. Allen is buried at Chillicothe. Allen County, Kansas is named for William Allen. In 1887, Ohio donated a statue of Allen to the National Statuary Hall Collection, exhibited in the National Statuary Hall of the U. S. Capitol; the statue was sculpted by Charles H. Niehaus. In 2010, the Ohio Historical Society held a statewide poll on the suitability of Allen as a distinguished representative of the state; the poll found. On August 26, the Ohio National Statuary Committee voted to replace Allen's statue with a statue of Ohio-born inventor Thomas Edison; the Ohio General Assembly agreed to replace the statue in part because "Allen’s pro-slavery position and outspoken criticism of President Abraham Lincoln during the Civil War make him a poor representative for Ohio in the U. S. Capitol." However, lack of funding for the Edison statue delayed replacement of the Allen statue. The Edison statue was completed in spring 2015, was installed on September 20, 2016.

The statue of Allen was relocated to the Ross County Heritage Center in Chillicothe. United States Congress. "William Allen". Biographical Directory of the United States Congress. National Statuary Hall Collection: William Allen at Architect of the Capitol William Allen at Ohio History Central William Allen at Find a Grave "Allen, William". Appletons' Cyclopædia of American Biography. 1900

Familial hypercholesterolemia

Familial hypercholesterolemia is a genetic disorder characterized by high cholesterol levels very high levels of low-density lipoprotein, in the blood and early cardiovascular disease. Since the underlying body biochemistry is different in individuals with FH, their high cholesterol levels are less responsive to the kinds of cholesterol control methods which are more effective in people without FH. Treatment is effective. FH is classified as a type 2 familial dyslipidemia. There are five types of familial dyslipidemia, each are classified from both the altered lipid profile and by the genetic abnormality. For example, high LDL is type 2. Others include defects in chylomicron metabolism, triglyceride metabolism, metabolism of other cholesterol-containing particles, such as VLDL and IDL. About 1 in 100 to 200 people have mutations in the LDLR gene that encodes the LDL receptor protein, which removes LDL from the circulation, or apolipoprotein B, the part of LDL that binds with the receptor. People who have one abnormal copy of the LDLR gene may develop cardiovascular disease prematurely at the age of 30 to 40.

Having two abnormal copies may cause severe cardiovascular disease in childhood. Heterozygous FH is a common genetic disorder, inherited in an autosomal dominant pattern, occurring in 1:500 people in most countries. Heterozygous FH is treated with statins, bile acid sequestrants, or other lipid-lowering agents that lower cholesterol levels. New cases are offered genetic counseling. Homozygous FH does not respond to medical therapy and may require other treatments, including LDL apheresis and liver transplantation. High cholesterol levels do not cause any symptoms. Yellow deposits of cholesterol-rich fat may be seen in various places on the body such as around the eyelids, the outer margin of the iris, in the tendons of the hands, elbows and feet the Achilles tendon. Accelerated deposition of cholesterol in the walls of arteries leads to atherosclerosis, the underlying cause of cardiovascular disease; the most common problem in FH is the development of coronary artery disease at a much younger age than would be expected in the general population.

This may lead to angina pectoris or heart attacks. Less arteries of the brain are affected. Peripheral artery occlusive disease occurs in people with FH who smoke. Atherosclerosis risk is increased further with age and in those who smoke, have diabetes, high blood pressure and a family history of cardiovascular disease. 85% of individuals with this disorder have not been diagnosed and are not receiving lipid-lowering treatments. Physical examination findings can help a physician make the diagnosis of FH. Tendon xanthomas are pathognomonic for the condition. A xanthelasma or corneal arcus may be seen; these common signs are non-specific findings. Cholesterol levels may be determined as part of health screening for health insurance or occupational health, when the external physical signs such as xanthelasma, arcus are noticed, symptoms of cardiovascular disease develop, or a family member has been found to have FH. A pattern compatible with hyperlipoproteinemia type IIa on the Fredrickson classification is found: raised level of total cholesterol, markedly raised level of low-density lipoprotein, normal level of high-density lipoprotein, normal level of triglycerides.

Total cholesterol levels of 350–550 mg/dL are typical of heterozygous FH while total cholesterol levels of 650–1000 mg/dL are typical of homozygous FH. The LDL is above the 75th percentile, that is, 75% of the healthy population would have a lower LDL level. Cholesterol levels can be drastically higher in people with FH who are obese. On the basis of the isolated high LDL and clinical criteria, genetic testing for LDL receptor mutations and ApoB mutations can be performed. Mutations are detected in between 80 % of cases. FH needs to be distinguished from familial combined hyperlipidemia and polygenic hypercholesterolemia. Lipid levels and the presence of xanthomata can confirm the diagnosis. Sitosterolemia and cerebrotendineous xanthomatosis are two rare conditions that can present with premature atherosclerosis and xanthomas; the latter condition can involve neurological or psychiatric manifestations, cataracts and skeletal abnormalities. The most common genetic defects in FH are LDLR mutations, ApoB mutations, PCSK9 mutations (less

Al gran sole carico d'amore

Al gran sole carico d'amore is an opera with music by Luigi Nono, based on plays by Bertolt Brecht, but incorporating texts of Fidel Castro, Che Guevara, Karl Marx, Vladimir Lenin. Nono himself and Yuri Lyubimov wrote the libretto, it premiered at the Teatro alla Scala on 4 April 1975. Lyubimov directed the original production; the UK premiere was at the 32nd Edinburgh Festival in 1978. In addition to vocal soloists and orchestra, the work incorporates taped sounds; this work is a product of Nono's strong political activism through the mid-1970s. Tania Thiers Favre Louise Michel L’ufficiale, the official Il soldato, the soldier Bismarck La madre, the mother Deola Pavel Il direttore di una fabbrica russa del 1905, the manager of a Russian factory in 1905 Il delatore, the police informer Haydée Una madre e donne vietnamite, a mother and Vietnamese women Gramsci Dimitrov Castro Male and female communards, comrades, the people of Paris, modern workers, Sicilian immigrants, Cuban women, prisoners The story is without conventional linear narrative, comments in its two parts on the 1871 Paris Commune and the 1905 Russian Revolution.

The principal characters are women from those periods, who perish in an attempt to stop the violence of their times. Teldec New Line 8573-81059-2: Claudia Barainsky, Maraile Lichdi, Melinda Liebermann, Stella Kleindienst, Lani Poulson, Roderic Keating, Markus Marquardt, Peter Kajlinger, Urs Winter, Helmut Holzapfel, Mark Munkittrick, Carsten Wittmoser. Recorded June–July 1999 in the Staatstheater Stuttgart. David Osmond-Smith. "Al gran sole carico d'amore". Grove Music Online. Oxford Music Online. Oxford University Press. E. G. "Al gran sole carico d’amore di Luigi Nono", in Piero Gelli Dizionario dell'opera, Baldini Castoldi Dalai, 2008. ISBN 88-6073-184-4

TVNZ 6

TVNZ 6 was a digital-only, commercial-free television channel operated by Television New Zealand. It launched in September 2007, was available in 60.3% of New Zealand homes on the Freeview and SKY Television Digital platforms. TVNZ 6 was on air daily from 6AM to 12 Midnight; the name TVNZ 6 was chosen because it was numeric, was deemed to allow'a broader content structure than any descriptive title', matches the number assigned to it on the Freeview electronic programme guide. TVNZ 6 showed pre-school programs during the Kidzone block from 6am to 6pm; until its closure at the end of June 2012, TVNZ 7 aired Kidzone from 6am to 8am. Kidzone received a 24-hour channel on Sky TV called Kidzone24; the channel played family programmes after Kidzone until closedown at midnight. At the start of TVNZ 6's launch the public service channel had structured its daily schedule as 3 separate services titled: TVNZ Kidzone, TVNZ Family, TVNZ Showcase. TVNZ 6 ceased broadcasting on 28 February 2011 and was replaced on 13 March 2011 by TVNZ U, a "social" channel targeted at 15- to 24-year olds.

Kidzone, Shortland Street: From the Beginning and other TVNZ 6 content moved to sister channels TVNZ 7, TVNZ Heartland and TVNZ Kidzone24. TVNZ U was advertiser-supported and ran from midday to midnight

Games People Play (Modern Family)

"Games People Play" is the 23rd episode of the fourth season of the American sitcom Modern Family, the series' 95th episode overall. It was aired on May 15, 2013; the episode was written by Ben Karlin based on a story by Danny Zuker and it was directed by Alisa Statman. Phil gets a new RV after selling a house and he wants to go to Yellowstone National Park for the summer, so he takes everyone on a test-drive just to get a taste of what the trip will be like. Claire believes that the trip with an RV is not a good idea because she knows that having all the kids together in the same place can turn into a disaster. Without saying anything to Phil, since she is always the one saying "no" to his ideas, she lets him discover it by himself. Things though are not going the way. In the meantime, Manny tries to find his backpack. Gloria breaks-in the house along with Jay to search for it. Instead of that and Jay end up snooping through Phil and Claire's stuff, something that they do at Mitch and Cameron's house since Manny remembers that his backpack is not in Luke's room but at Mitch and Cam's house instead.

While snooping around, they find out that they were not invited to a games' night and they start wondering why Mitch and Cam would not invite them. What they do not know is that they were invited but Manny forgot to give them the invitation. Meanwhile, Lily participates at a gymnastics competition and she is doing great. Cam and Mitch's competitive spirits, make the parents of the other kids turn on them. In its original American broadcast, "Games People Play" was watched by 10.03 million. "Games People Play" received positive reviews. Leigh Raines from TV Fanatic rated the episode 4.5/5. "The Pritchett clan ranks high among TV's most competitive families. In "Games People Play," we saw just how much their competitive nature can rub off on other loved ones."Michael Adams of 411mania gave the episode 8/10 saying that the episode was "just so enjoyable". "Not too much going on, no real craziness, just 3 simple story-lines that all had funny moments. This is what a sitcom should be."Donna Bowman of The A.

V. Club gave a B grade to the episode. Despite the good reviews, Zack Dionne from Vulture rated the episode only with 2/5 stating that last week's family affair at the roller rink is a tough act to follow. "Games People Play" on IMDb "Games People Play" at TV.com "Games People Play" at ABC.com

Sheboygan South High School

Sheboygan South High School is a public coeducational high school serving 1,335 students in grades 9-12. Located on the south side of Sheboygan, Wisconsin, it is part of the Sheboygan Area School District; the school has a rivalry with the cross-town Sheboygan North High School. The school opened in 1960 in the midst of a population shift toward the south side of Sheboygan and the Town of Wilson, it was a replacement for the former Sheboygan Central High School, located in the city's downtown, which remains the site of the school district's offices and the site of several alternative programs. The school has undergone two expansions. In 1998, a new library and classrooms were added, a more significant expansion occurred in 2005-2006, with the addition of more classrooms, a new indoor athletic complex, new tennis courts. Naming rights for the school's new gymnasium were acquired by Acuity Insurance, with the weight room/fitness center being sponsored by Aurora Health Care and open to use by the public outside of school hours.

In June 2017, after the school's office facilities moved to the southern part of the building, its address was changed to 1240 Washington Avenue, ending 57 years of holding the 3128 South 12th Street address. In the recent past, the Acuity Gymnasium played host to a private Fifth Harmony concert on March 19, 2014 sponsored by Milwaukee radio station WXSS and won by South High students in a school spirit contest involving clothing donations to Goodwill Industries, it played host to a Bernie Sanders rally for his 2016 presidential campaign on April 1 of that year. The school's athletic teams are nicknamed the Redwings, with the school colors being red and black; until 1993 the nickname was the Redmen, carried over from Central. When concerns over the racial implications of the Native American name were broached, a long debate among students, faculty and the community at large resulted in a change, one of the first in the state of Wisconsin to be settled long before the May 2010 implementation of a state law allowing easier challenges of Native American nicknames, one of the first computer-designed high school logos in the pre-Internet age of desktop publishing.

One remnant of the former Redmen name still exists in a mosaic profile of an Indian chief on the front facade of the school's auditorium. The school's newspaper and yearbook are named a carryover from Central High School. Three members of the faculty hold National Board of Teaching Certification. Bill Schroeder, professional football player Roy Pirrung, ultramarathoner WSHS-FM Sheboygan South High School Old Sheboygan South High School Yearbook Senior Photos