William Duesbury (1725–1786) was an English enameller, in the sense of a painter of porcelain, who became an important porcelain entrepreneur, founder of the Royal Crown Derby and owner of porcelain factories at Bow, Chelsea, Derby and Longton Hall.

The Bow porcelain factory was an emulative rival of the Chelsea porcelain factory in the manufacture of early soft-paste porcelain in Great Britain. The two London factories were the first in England. It was originally located near Bow, in what is now the London Borough of Tower Hamlets, but by 1749 it had moved to "New Canton", sited east of the River Lea, and then in Essex, now in the London Borough of Newham.