Major General William Holmes was a senior Australian Army officer during the First World War. He was mortally wounded by a German artillery shell while surveying the ground won at the Battle of Messines.

General Holmes Drive is a 5-kilometre (3.1 mi) major divided road located in Sydney, New South Wales, Australia. The road forms part of the M1, the A1, the Sydney Orbital Network, and the Australian Highway 1 network. Initially built in 1919 as a two-lane road and duplicated in 1951, the road partially circumnavigates Sydney Airport with its north-eastern terminus in Mascot, heading west and then south and then south-west, with its south-western terminus with The Grand Parade in Brighton-Le-Sands.