Sir William More, of Loseley, Surrey, was the son of Sir Christopher More. The great house at Loseley Park was built for him, which is still the residence of the More Molyneux family. Of Protestant sympathies, as Sheriff and Vice-Admiral of Surrey he was actively involved in local administration of the county of Surrey and in the enforcement of the Elizabethan religious settlement, and was a member of every Parliament during the reign of Queen Elizabeth I. He was the owner of property in the Blackfriars in which the first and second Blackfriars theatres were erected. He has been described as "the perfect Elizabethan country gentleman" on account of his impeccable character and his assiduity and efficiency of service.

Loseley Park is a large Tudor manor house with later additions and modifications 3 miles (4.8 km) south-west of Guildford, Surrey, England, in Artington close to the hamlet of Littleton. The estate was acquired by the direct ancestors of the current owners, the More-Molyneux family, at the beginning of the 16th century. The house built for Sir William More is a Grade I listed building, the highest rank in architecture or heritage. Loseley appears in the Domesday Book of 1086 as Losele. It was held by Turald (Thorold) from Roger de Montgomery. Its Domesday assets were: 2 hides. It had 4 ploughs, 5 acres (20,000 m2) of meadow. It rendered £3. The papers of Sir Thomas Cawarden, Master of the Revels, were formerly preserved in the house. Loseley Park is still the residence of the More-Molyneux family and is open to the public. The 17th-century tithe barn is available for weddings.