William Walter Jefferis was an American mineralogist and curator of the William S. Vaux Collection of minerals and artifacts at the Philadelphia Academy of Natural Sciences from 1883 to 1898. He personally collected and cataloged 35,000 mineral specimens, which he sold to the Carnegie Museum of Natural History in 1905.

The Academy of Natural Sciences of Drexel University, formerly the Academy of Natural Sciences of Philadelphia, is the oldest natural science research institution and museum in the Americas. It was founded in 1812, by many of the leading naturalists of the young American republic with an expressed mission of "the encouragement and cultivation of the sciences". It has sponsored expeditions, conducted original environmental and systematics research, and amassed natural history collections containing more than 17 million specimens. The Academy also organizes public exhibits and educational programs for both schools and the general public.