The Williams-Wynn Baronetcy, of Gray's Inn in the County of Middlesex was created in the Baronetage of England on 6 July 1688 for William Williams, a prominent Welsh politician and lawyer from Anglesey, Wales. A member of the family, Sir Watkin, became one of the richest men in Britain.

Sir William Williams, 1st Baronet was a Welsh lawyer and politician. He served as a Member of Parliament for Chester and later Beaumaris, and was appointed Speaker for two English Parliaments during the reign of Charles II. He later served as Solicitor General during the reign of James II. Williams had a bitter personal and professional rivalry with Judge Jeffreys.