Williams Carter Wickham was a Virginia lawyer and politician. A plantation owner who served in both houses of the Virginia General Assembly, Wickham also became a delegate to the Virginia Secession Convention of 1861, where he voted against secession, but after fellow delegates and voters approved secession, he joined the Confederate States Army and rose to the rank of cavalry general, then became a Confederate States Congressman near the end of the American Civil War. Later, Wickham became a Republican and helped rebuild Virginia's infrastructure after gaining control of the heavily damaged Virginia Central Railroad, which he repaired and helped merge into the Chesapeake and Ohio Railway company. Cooperating with financier Collis Huntington, Wickham developed coal resources and the Newport News Shipyard. He was also again elected to the Virginia Senate. His son Henry T. Wickham also became a lawyer and would work with his father and eventually twice become the speaker pro tempore of the Virginia Senate.

The Virginia Secession Convention of 1861 was called in the state capital of Richmond to determine whether Virginia would secede from the United States, govern the state during a state of emergency, and write a new Constitution for Virginia, which was subsequently voted down in a referendum under the Confederate Government.