Wilopo was an Indonesian politician and lawyer. A capable administrator, he served as prime minister of Indonesia from 1952 to 1953. He also held various other positions during his career, including as Minister of Labor, Minister of Economic Affairs, speaker of the Constitutional Assembly, and chairman of the Supreme Advisory Council.

The Prime Minister of the Republic of Indonesia was a political office in Indonesia which existed from 1945 until 1966. During this period, the prime minister was in charge of the cabinet of Indonesia, one of the three branches of government along with the People's Representative Council and the president. Following his 1959 decree, President Sukarno assumed the role and powers of prime minister until his resignation in 1966.