Winnie Winkle is an American comic strip published during a 76-year span (1920–1996). Ten film adaptations were also made. Its premise was conceived by Joseph Medill Patterson, but the stories and artwork were by Martin Branner, who wrote the strip for over 40 years. It was one of the first comic strips about working women. The main character was a young woman who had to support her parents and adopted brother, serving as a reflection of the changing role of women in society. It ran in more than 100 newspapers and translations of the strip's Sunday pages were made available in Europe, focusing on her little brother Perry Winkle and his gang.

Martin Michael Branner, known to his friends as Mike Branner, was a cartoonist who created the comic strip Winnie Winkle.