The Winston-Salem Northern Beltway is a partially completed freeway loop around the city of Winston-Salem in North Carolina. The western section has been designated as North Carolina Highway 452 (NC 452), which will become I-274 when completed, and the eastern section of the beltway will be designated as North Carolina Highway 74 (NC 74), which will become part of I-74 when completed. The entire route is in Forsyth County.

Interstate 74 (I-74) is a partially completed part of the Interstate Highway System that is planned to run from Davenport, Iowa, to Myrtle Beach, South Carolina. In the US state of North Carolina, I-74 currently exists in three distinct segments; from I-77 at the Virginia state line to US Highway 52 (US 52) near Mount Airy, from I-40 in Winston-Salem to US 220 near Ellerbe, and from US 74 and US 74 Business near Maxton to US 74/North Carolina Highway 41 (NC 41) near Lumberton. I-74 has an extensive concurrency with I-73 from Randleman to Ellerbe in the Piedmont. When completed, I-74 will link the cities of Mount Airy, Winston-Salem, High Point, Rockingham, Laurinburg, and Lumberton.