The 10th Senate district of Wisconsin is one of 33 districts in the Wisconsin Senate. Located in northwest Wisconsin, the district comprises all of Buffalo, Pepin, Pierce, and St. Croix counties, along with most of Trempealeau and parts of western Dunn County. It continas the cities of Hudson, Arcadia, New Richmond, Prescott, Mondovi, Blair, Independence, Buffalo City, Fountain City, and River Falls. It also contains landmarks such as Kinnickinnic State Park, Perrot State Park, Trempealeau National Wildlife Refuge, and part of the Saint Croix National Scenic Riverway.

The 29th Assembly District of Wisconsin is one of 99 districts in the Wisconsin State Assembly. Located in western Wisconsin, the district comprises all of Buffalo and Pepin counties, along with most of Pierce County, and much of Trempealeau County. It includes the cities of Alma, Arcadia, Blair, Buffalo City, Durand, Fountain City, Independence, Mondovi, Prescott, and Whitehall. The district also contains Trempealeau National Wildlife Refuge and Perrot State Park. The district is represented by Republican Clint Moses, since January 2021.