Wise is a town in Wise County, Virginia. The population was 2,970 at the 2020 census. It is the county seat of Wise County. It was originally incorporated as the town of Gladeville in 1874. The town's

Wise County is a county located in the U.S. state of Virginia. The county was formed in 1856 from Lee, Scott, and Russell Counties and named for Henry A. Wise, who was the Governor of Virginia at the