Wolli Creek railway station is located at the junction of the Airport and Illawarra lines, serving the Sydney suburb of Wolli Creek. It is served by Sydney Trains T4 Illawarra line, T8 Airport & South line services and NSW TrainLink South Coast line services.

The Airport Link is Sydney's inner-southern railway line connecting Sydney Airport to the central business district and the south-western suburbs of Sydney. With the exception of Wolli Creek, the Airport Line stations are operated by a private company, the Airport Link Company, as part of a public private partnership. The contract, which expires in 2030, allows the company to charge a surcharge on top of the normal fare. The line is served by Sydney Trains T8 Airport & South line services.