The Wye Valley is the limestone valley of the River Wye in the White Peak of Derbyshire, England. The source of the River Wye is west of Buxton on Axe Edge Moor. One main channel runs underground through Poole's Cavern. The river flows though Buxton Pavilion Gardens and then along a culvert under the town centre. After leaving the flat area of central Buxton, the Wye Valley becomes distinct as a gorge running east for 10 miles (16 km) before the valley broadens at Ashford-in-the Water.

The River Wye is a limestone river in the Peak District of Derbyshire, England. It is 22 miles long, and is one of the major tributaries of the River Derwent, which flows into the River Trent, and ultimately into the Humber and the North Sea.