Wynnewood is a city in Garvin County, Oklahoma, United States. It is 67 miles (108 km) south of Oklahoma City. The population was 1,927 at the time of the 2020 census. Located in what was then the Chickasaw Nation of Indian Territory, it began as a village called "Walner" in 1886, on the proposed route of the Gulf, Colorado and Santa Fe Railway. Railroad workers from Pennsylvania named the community for Wynnewood, a community outside of Philadelphia. The name became official on April 6, 1887.

Garvin County is a county in south-central Oklahoma, United States. As of the 2020 census, the population was 25,656. Its county seat is Pauls Valley. In 1906, delegates to Constitution Convention formed Garvin County from part of the Chickasaw Nation, Indian Territory. The county was named for Samuel J. Garvin, a local Chickasaw rancher, merchant and banker. Its economy is largely based on farming, ranching and oil production.