The Xavier Musketeers men's basketball team represents Xavier University in Cincinnati, Ohio. The school's team currently competes in the Big East Conference, and are coached by Sean Miller. Xavier has appeared in the NCAA tournament 29 times, 16 times in the 18 tournaments between 2001 and 2018. On March 11, 2018, Xavier earned its first ever No. 1 seed in the NCAA Tournament. Xavier is also a two-time winner of the NIT, with their most recent championship coming in 2022.

Xavier University is a private Jesuit university in Cincinnati, Ohio. It is the sixth-oldest Catholic and fourth-oldest Jesuit university in the United States. Xavier has an undergraduate enrollment of 4,860 students and graduate enrollment of 1,269 students. The school's system comprises the main campus in Cincinnati, Ohio, as well as regional locations for the Accelerated Bachelor of Science in Nursing (ABSN) program in Columbus and Cleveland.