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Xbox is a video gaming brand created and owned by Microsoft. It represents a series of video game consoles developed by Microsoft, with three consoles released in the sixth and eighth generations, respectively; the brand represents applications, streaming services, an online service by the name of Xbox Live, the development arm by the name of Xbox Game Studios. The brand was first introduced in the United States in November 2001, with the launch of the original Xbox console; the original device was the first video game console offered by an American company after the Atari Jaguar stopped sales in 1996. It reached over 24 million units sold as of May 2006. Microsoft's second console, the Xbox 360, was released in 2005 and has sold 84 million units as of June 2014; the Xbox One has been released in 21 markets in total, with a Chinese release in September 2014. The head of Xbox is Phil Spencer, who succeeded former head Marc Whitten in late-March 2014; the original Xbox was released on November 15, 2001, in North America, February 22, 2002, in Japan, March 14, 2002, in Australia and Europe.

It was Microsoft's first foray into the gaming console market. As part of the sixth-generation of gaming, the Xbox competed with Sony's PlayStation 2, Sega's Dreamcast, Nintendo's GameCube; the Xbox was the first console offered by an American company after the Atari Jaguar stopped sales in 1996. The name Xbox was derived from a contraction of DirectX Box, a reference to Microsoft's graphics API, DirectX; the integrated Xbox Live service launched in November 2002 allowed players to play games online with or without a broadband connection. It first competed with Dreamcast's online service but primarily competed with PlayStation 2's online service. Although these two are free while Xbox Live required a subscription, as well as broadband-only connection, not adopted yet, Xbox Live was a success due to better servers, features such as a buddy list, milestone titles like Halo 2 released in November 2004, the best-selling Xbox video game and was by far the most popular online game for the system; the Xbox 360 was released as the successor of the original Xbox in November 2005, competing with Sony's PlayStation 3 and Nintendo's Wii as part of the seventh generation of video game consoles.

As of June 30, 2013, 78.2 million Xbox 360 consoles have been sold worldwide. The Xbox 360 was unveiled on MTV on May 12, 2005, with detailed launch and game information divulged that month at the Electronic Entertainment Expo; the console sold out upon release in all regions except in Japan. Several retail configurations of the core Xbox 360 model were offered over its lifetime, varying the amount of RAM and internal storage offered; the Xbox 360 showed an expanded Xbox Live service, the ability to stream multimedia content from PCs, while updates added the ability to purchase and stream music, television programs, films through the Xbox Music and Xbox Video services, along with access to third-party content services through third-party media streaming applications. Microsoft released Kinect, a motion control system for the Xbox 360 which uses an advanced sensor system. Two major revisions of the Xbox 360 were released following the initial launch; the Xbox 360 S, launched in 2010, featured the same core hardware but with a redesigned, slimmer form factor with a smaller-sized 250 GB hard drive.

It added integrated 802.11 b/g/n Wi-Fi, TOSLINK S/PDIF optical audio output, five USB 2.0 ports and special port designed for the Kinect peripheral. The Xbox 360 S replaced the base Xbox 360 unit, discontinued, sold at the same price.. A cheaper Xbox 360 S unit, removing the 250 GB drive while adding 4 GB of internal store, was released in 2010; the second major revision of the Xbox 360 was the Xbox 360 E, released in 2013. It featured a case style similar to the upcoming Xbox One, eliminated one USB port and the S/PDIF, YPbPr component and S-video connections, but otherwise shared the same specifications as the Xbox 360 S; the Xbox One was released on November 22, 2013, in North America, as the successor of the Xbox 360. The Xbox One competes with Sony's PlayStation 4 and Nintendo's Wii U and Switch as part of the eighth generation of video game consoles. Announced on May 21, 2013, the Xbox One has an emphasis on internet-based features, including the ability to record and stream gameplay, the ability to integrate with a set-top box to watch cable or satellite TV through the console with an enhanced guide interface and Kinect-based voice control.

Following its unveiling, the Xbox One proved controversial for its original digital rights management and privacy practices. After an overwhelmingly negative response from critics and consumers, Microsoft announced that these restrictions would be dropped. Microsoft was criticized for requi

Frank W. Wadsworth

Frank W. Wadsworth was an American Shakespearean scholar and sportsman, he was born in New York City, the son of Prescott Kingsley Wadsworth and Elizabeth Browning Wadsworth. He graduated from the Kent School in 1938 and served as a naval aviator in WWII. After the war he completed his A. B. degree at Princeton University, as well as his M. A. and Ph. D, he served on the faculty teaching English literature at the University of Los Angeles. He served as a member of the Selection Committee for The Woodrow Wilson National Fellowship Foundation, he was named a John Simon Guggenheim Memorial Foundation Fellow in 1961, was the recipient of numerous academic awards and honors, including a Woodrow Wilson Fellowship, Folger Shakespeare Library Fellow, honorary Phi Beta Kappa. Wadsworth was a trustee of the Wenner-Gren Foundation for Anthropological Research from 1970 to 2006, an organization supporting anthropological research, served as Chairman of the Board from 1977 to 1987. In recognition of his commitment to the scholarly integrity of anthropology, the Foundation renamed the Professional Development International Fellowship the Wadsworth Fellowship Program.

His hobbies included horseback sailing. He is buried in Vermont. Wadsworth was best known to the public for his The Poacher from Stratford, a popular defense of Shakespeare’s authorship and the first such book written by an academic Shakespearean scholar, he thought that Shakespeare scholars should not dismiss the claims of those who believe that someone other than Shakespeare wrote the canon, that treating the subject with silence worked instead to encourage rather than discourage such theories. Thirty-five years he reviewed the field in an article published in the Shakespeare Newsletter, "The Poacher Re-Visited," in which he wrote: It is important that we recognize the iconoclasts those of us who are teachers, but as Shakespeareans … we should not do it by visiting upon them the disdain of the past but by letting them speak for themselves … Our role should be not to suppress debate but to instruct students how to consider the Oxfordians’ arguments and thoughtfully. That exercise will make students not just more responsible as far as Shakespeare is concerned, but wiser, more critical, more judicial, in dealing with the complex challenges they will face in the difficult decades which lie ahead of them.

We demystify authorship controversies, assassination conspiracies, theories of extra-terrestrial shindigs painful social demands, by letting their proponents speak out, not by censoring them. At least that's, and still do. The White Devil: An Historical and Critical Study. Princeton University Press, 1951. "The Relationship of Lust’s Dominion and John Mason’s The Turke." ELH 20:3, 1953. "'Sound and Fury'—King Lear on Television." Quarterly of Film and Television 8:3, 1954. "The Revenger’s Tragedy" MLA Review, 1955. "Orwell as a Novelist: The Early Work". University of Kansas Review, 12:2, 1955. "Webster's Duchess of Malfi in the Light of Some Contemporary Ideas on Marriage and Remarriage". Philological Quarterly, 35:4, 1956; the Poacher from Stratford: A Partial Account of the Controversy over the Authorship of Shakespeare's Plays. California University Press. "Hamlet and Iago: Nineteenth-Century Breeches Parts". Shakespeare Quarterly 17:2, 1966. "Some Nineteenth-Century Revivals of The Duchess of Malfi", Theatre Survey, 8.2 "'Shorn and Abated'–British Performances of The Duchess of Malfi".

Theatre Survey 10:2, 1969 "University Teaching—The State of the Art". Metaphilosophy, 3:1, 1972. "William Shakespeare", World Book Encyclopedia, 1989. Frank Wadsworth. Obituary; the New York Times, 15 August 2012. Wenner-Gren Foundation for Anthropological Research Wadsworth Fellowship Program


Hypopituitarism is the decreased secretion of one or more of the eight hormones produced by the pituitary gland at the base of the brain. If there is decreased secretion of one specific pituitary hormone, the condition is known as selective hypopituitarism. If there is decreased secretion of most or all pituitary hormones, the term panhypopituitarism is used; the signs and symptoms of hypopituitarism vary, depending on which hormones are undersecreted and on the underlying cause of the abnormality. The diagnosis of hypopituitarism is made by blood tests, but specific scans and other investigations are needed to find the underlying cause, such as tumors of the pituitary, the ideal treatment. Most hormones controlled by the secretions of the pituitary can be replaced by tablets or injections. Hypopituitarism is a rare disease, but may be underdiagnosed in people with previous traumatic brain injury; the first description of the condition was made in 1914 by the German physician Dr Morris Simmonds.

The hormones of the pituitary have different actions in the body, the symptoms of hypopituitarism therefore depend on which hormone is deficient. The symptoms may be subtle and are initially attributed to other causes. In most of the cases, three or more hormones are deficient; the most common problem is insufficiency of follicle-stimulating hormone and/or luteinizing hormone leading to sex hormone abnormalities. Growth hormone deficiency is more common in people with an underlying tumor than those with other causes. Sometimes, there are additional symptoms. Headaches may accompany pituitary tumors, as well as pituitary apoplexy and lymphocytic hypophysitis. Apoplexy, in addition to sudden headaches and worsening visual loss, may be associated with double vision that results from compression of the nerves in the adjacent cavernous sinus that control the eye muscles. Pituitary failure results in many changes in the skin and nails as a result of the absence of pituitary hormone action on these sites.

Several hormone deficiencies associated with hypopituitarism may lead to secondary diseases. For instance, growth hormone deficiency is associated with obesity, raised cholesterol and the metabolic syndrome, estradiol deficiency may lead to osteoporosis. While effective treatment of the underlying hormone deficiencies may improve these risks, it is necessary to treat them directly. Deficiency of all anterior pituitary hormones is more common than individual hormone deficiency. Deficiency of luteinizing hormone and follicle-stimulating hormone, together referred to as the gonadotropins, leads to different symptoms in men and women. Women experience oligo - or infertility. Men lose facial and trunk hair, as well as suffering decreased muscle mass and anemia. Both sexes may experience a decrease in libido and loss of sexual function, have an increased risk of osteoporosis. Lack of LH/FSH in children is associated with delayed puberty. Growth hormone deficiency leads to a decrease in muscle mass, central obesity and impaired attention and memory.

Children experience short stature. Adrenocorticotropic hormone deficiency leads to adrenal insufficiency, a lack of production of glucocorticoids such as cortisol by the adrenal gland. If the problem is chronic, symptoms consist of fatigue, weight loss, failure to thrive, delayed puberty, hypoglycemia and hyponatremia. If the onset is abrupt, collapse and vomiting may occur. ACTH deficiency is similar to primary Addison's disease, cortisol deficiency as the result of direct damage to the adrenal glands. Thyroid-stimulating hormone deficiency leads to hypothyroidism. Typical symptoms are tiredness, intolerance to cold, weight gain, hair loss and slowed thinking, as well as a slowed heart rate and low blood pressure. In children, hypothyroidism leads to delayed growth and in extreme inborn forms to a syndrome called cretinism. Prolactin plays a role in breastfeeding, inability to breastfeed may point at abnormally low prolactin levels. Antidiuretic hormone deficiency leads to the syndrome of diabetes insipidus: inability to concentrate the urine, leading to polyuria, low in solutes, dehydration and—in compensation—extreme thirst and constant need to drink, as well as hypernatremia.

ADH deficiency may be masked if there is ACTH deficiency, with symptoms only appearing when cortisol has been replaced. Oxytocin deficiency causes few symptoms, as it is only required at the time of childbirth and breastfeeding; the pituitary gland is located at the base of the brain, intimately connected with the hypothalamus. It consists of two lobes: the posterior pituitary, which consists of nervous tissue branching out of the hypothalamus, the anterior pituitary, which consists of hormone-producing epithelium. T

Becca Balint

Rebecca A. "Becca" Balint is a Vermont educator and politician. A Democrat, she has served in the Vermont Senate since 2015. Since 2017, she has served as the Senate Majority Leader. Balint was born circa 1968 at the United States Army hospital in Heidelberg while her father was a U. S. Army captain in Germany, her father immigrated to the United States as a child, after his father was killed during the Holocaust. In addition to serving in the U. S. Army, Balint's father worked at a phone company. Balint's mother worked at a watch factory and earned both a college degree and a black belt in kung fu. Balint was raised in Upstate New York, attended public schools in Peekskill. In 1994, Balint moved to Plymouth, for a job as a rock-climbing instructor at Farm & Wilderness summer camp, she became a full-time Vermont resident in 1997. Balint was on the crew team as a coxswain at Barnard College, was captain of the crew team at Smith College. Balint remains interested in athletics, is an avid runner. Balint and her wife, attorney Elizabeth R. Wohl, met in 2000 at Wilderness.

They live in Brattleboro with a son and a daughter. Balint attended Barnard College of Columbia University for two years, in 1990 received her bachelor of arts degree in history and women's studies from Smith College, where she graduated magna cum laude and Phi Beta Kappa. In 1995, Balint earned a master of education degree from Harvard University, in 2001 she received a master of arts in history from the University of Massachusetts Amherst. Balint is a 2013 graduate of The Campaign School at Yale University and a 2014 graduate of the inaugural class of Emerge Vermont. After graduating college in 1990, Balint worked minimum wage jobs in bakeries and cafes in Massachusetts. Balint moved to Vermont in 1994 to teach rock climbing at the Farm and Wilderness Foundation in Plymouth, became a full-time resident of Vermont in 1997, she went on to direct Saltash Mountain Camp at Farm & Wilderness in Mount Holly, a coed wilderness adventure camp for children ages 11 to 15. Balint has taught in public and private schools throughout New England, at the Community College of Vermont.

When her two children were young, she worked at home as a full-time caregiver. Balint has served on the workforce committee of the Southeastern Vermont Economic Development Strategies, she is a Coaches Training Institute-trained coach. Balint writes a weekly op-ed column in the Brattleboro Reformer, on subjects ranging from politics, to nature, to parenting, she has written for other publications. Balint is a frequent public speaker, for example at the 2019 climate strike demonstration in Burlington, Vermont. Balint has been a State Senator from Windham County since 2015, Senate Majority Leader since 2017. Balint serves on the Senate Economic Development and General Affairs Committee, to which she was appointed in 2015, she serves on the Committee on Finance, the Senate Rules and Joint Rules Committees, the Legislative Committee on Judicial Rules. Balint has chaired the Senate Sexual Harassment Prevention Panel since 2017. During her first term, Balint served on the Institutions Committee. During her second term, Balint served as vice chair of the Education Committee.

At the start of her second term in January 2017, Balint was elected as the State Senate's Majority Leader, succeeding Phil Baruth, who did not seek another term in the position. At the start of the 2019 legislative session, Balint was re-elected as Majority Leader. During her time as State Senator, Balint has earned a reputation for being "iberal but pragmatic, with a particular interest in social justice and anti-poverty efforts." As Majority Leader, she has a reputation for running efficient caucus meetings. Balint is known for her mentorship of other women in politics. Balint was the first gay woman to serve in the Vermont Senate. Balint's legislative priorities have included: increasing affordable housing; as chair of the Senate Sexual Harassment Panel, Balint has worked to update the policy and the culture regarding sexual harassment in the Vermont State House. Prior to serving in the Senate, Balint served on Brattleboro's Development Review Board, was elected as a district representative to Brattleboro's town meeting.

Balint has been endorsed by the Vermont State Employees' Association, Vermont League of Conservation Voters, Union of Vermont Educators, Planned Parenthood, Gun Sense Vermont, the Victory Fund. In 2014, Balint was a candidate for the Vermont Senate from the two-member at-large Windham County district. 2014 Democratic Primary Election, State Senate, Windham CountyJeanette White, 40.1% Becca Balint, 29.9% Roger Allbee, 22% Joan Bowman, 7.9%2014 General Election, State Senate, Windham CountyJeanette White, 43.4% Becca Balint, 35.6% Mary Hasson, 11% Jerry Levy, 5% Aaron Diamondstone, 4.7%2016 Democratic Primary Election, State Senate, Windham CountyJeanette White, 50.4% Becca Balint, 48.9%2016 General Election, State Senate, Windham CountyJeanette White, 36.6% Becca Balint, 35.7% David Schoales, 17.9% Jerry Levy, 4.9% Aaron Diamondstone, 4.6%2018 Democratic Primary Election, State Senate, Windham CountyBecca Balint, 46.5% Jeanette White, 42.6% Wayne Vernon Estey, 10.6%2018 General Election, State Senate, Windham CountyBecca Balint, 39.4% Jeanette White, 36.6% Tyler Colford, 13.3% Beverly Stone, 5.8% Aaron Diamondst

Grand Trunk Western station (Lansing)

The Grand Trunk Western station was a historic railroad station in Lansing, Michigan. The station was listed as a Michigan State Historic Site in 1978, it was added to the National Register of Historic Places in 1980; the first rail line through Lansing was established in 1856 when the Detroit and Milwaukee Railroad constructed a line through the city. This was followed in 1872 by the Michigan Central Railroad and in 1879 by the Chicago and Grand Trunk Railway. By the early 1900s there were six separate rail lines through the city. After the Chicago and Grand Trunk Railway reorganized in 1900, they built a series of new depots along their line; when REO Motor Car Company announced the construction of a new plant along the Grand Trunk line, the railroad decided to construct their new depot near the new REO plant. Grand Trunk commissioned. Construction on the new depot was completed late that year, it served as a main depot for all passengers until 1971. In 1972, it was renovated as a restaurant; the building's exterior remains unchanged.

Gerald R. Ford, from Michigan and the 38th president of the United States, dined here during a campaign tour on May 15, 1976; the building was abandoned in the early 2000s. In 2010, the Lansing Board of Water & Light began construction of a powerplant adjacent to the depot, included a full restoration of the station in the project; the Lansing Grand Trunk Western station is a single story, rectangular Jacobethan style red-brick building on a gray ashlar foundation. It measures 107 feet long; the main entrance is housed in a two-story, ten-foot square brick tower, topped by a crenelated parapet. The roof is covered with red tile, has overhanging eaves; the window hoods, sills and gable copings are of Bedford limestone. At one end of the building is a waiting platform, covered with a gable roof supported by wooden posts. Michigan portal Railways portal Cosentino, Lawrence. "Depot Gets New Shot at History: BWL Gives REO Town's Grand Trunk Railroad Station $2.8 Million Makeover". City Pulse. Lansing

Neustadt (Weinstra├če) Hauptbahnhof

Neustadt Hauptbahnhof – called Neustadt a/d. Haardt until 1935 and from 1945 until 1950 – is the central station of in the city of Neustadt in the German state of Rhineland-Palatinate. In addition to the Hauptbahnhof, Rhine-Neckar S-Bahn services stop at Neustadt Böbig halt. Mußbach station and Neustadt halt, opened on 19 November 2013, are located in Neustadt; the station was opened on 11 June 1847 as the terminus of the first section of the Palatine Ludwig Railway from Rheinschanze to Bexbach. With the opening of the Palatine Maximilian Railway to Wissembourg in 1855 and the Palatine Northern Railway, built from 1865 to 1873, to Monsheim, it developed into a railway junction and became a stop for long-distance trains. Since the 2000s, its importance for long-distance traffic has fallen. Since 2003, it has been integrated into the network of the Rhine-Neckar S-Bahn. In addition, its entrance building is under heritage protection. Neustadt Hauptbahnhof is centrally located within Neustadt; the inner city adjoins it to the north and the Saalbau, an events and conference centre, is nearby.

To the south of the railway station is the Hambacher Höhe. Crossing the line to the west of the station is the German Wine Route, which winds through this area through an S-shaped curve. East of the facilities serving passengers, the railway crosses a bridge over Landauer Straße, which forms part of federal highway 39. To the east, past the freight yard, is the historical district of Branchweiler; the station is located at line-kilometre 77.203. The zero point for the kilometrage is between Bexbach and Neunkirchen on the former Bavaria–Prussia national border; the Mannheim–Saarbrücken railway, which developed out of the Palatine Ludwig, comes from the northeast. It reaches Neustadt Hauptbahnhof over a drawn out S-curve, which takes it pass the freight facilities and Neustadt-Böbig halt. Beyond the Hauptbahnhof, it runs to the west or northwest along the Speyerbach through the Palatinate Forest towards Saarbrücken, passing the suburbs of Afrikaviertel and Schöntal; the Maximilian Railway branches in the east from the line to Mannheim after the crossing over federal road 39 and runs along a long curve to the south towards Wissembourg.

The Palatine Northern Railway starts in the northern station area and runs to the Neustadt-Böbig halt parallel with the line to Mannheim and continues via Bad Dürkheim and Grünstadt to Monsheim. The narrow gauge Palatine Overland Railway, which existed between 1912 and 1955, began in the station forecourt and crossed the standard-gauge tracks a bridge it shared with the German Wine Route and passed through several wine-growing villages to Landau, it had been planned to build a railway running north-south in the Bavarian Circle of the Rhine. However, it was agreed to first build a railway running east-west, to be used for transporting coal from the Saar district to the Rhine. Two options were discussed for the general route through Kaiserslautern, as the development of a route through the Palatinate Forest proved to be complicated. At first the responsible engineers considered a route through the Dürkheim valley. However, this proved impractical because its side valleys were too low, above all the climb to Frankenstein would have been too high steep.

It would have required stationary steam engines and rope haulage to overcome the differences in altitude. For this reason, they chose an option through the Neustadt valley, which would be difficult to climb according to expert opinion, but would be feasible and, in contrast to the Dürkheim valley, would avoid the need for stationary steam engines. At the same time, plans were being made to build a railway line from Mainz to Neustadt, but these did not proceed; the tracks were laid between Rheinschanze and Neustadt from April 1846. Neustadt station’s entrance building was completed at the same time; the section was opened on 11 June 1847. The opening train, which began in Ludwigshafen, was hauled by the locomotive Haardt, numbered 1; the celebrations on site included cannon fire. On the platform were the state commissioner of Neustadt and some other subordinate officials; the return trip, in which these officials took part, set off at 1 pm. The completion of the Neustadt–Frankenstein section was delayed by difficulties in acquiring the land needed and the difficult topography.

For example, ten tunnels had to be built through foothills. The opening ceremony took place on 25 August 1849. At the same time as the Ludwig Railway was being built, plans were developed for a north-south link within the Palatinate, it was debated as to whether a route through the hills from Neustadt via Landau to Wissembourg or a route near the Rhine via Speyer, Germersheim and Wörth was more urgent and desirable. The military preferred a route on the edge of the Palatinate Forest. However, the political events of 1848 caused the project to come to a standstill. In January 1850, a brochure appeared in Neustadt that promoted a route via Landau to Wissembourg and argued that the line should serve the larger townships rather than those a