Yangzhou is a prefecture-level city in central Jiangsu Province, East China. Sitting on the north bank of the Yangtze, it borders the provincial capital Nanjing to the southwest, Huai'an to the north, Yancheng to the northeast, Taizhou to the east, and Zhenjiang across the river to the south. Its population was 4,559,797 at the 2020 census and its urban area is home to 2,635,435 inhabitants, including three urban districts, currently in the agglomeration.

Jiangsu is an eastern coastal province of the People's Republic of China. It is one of the leading provinces in finance, education, technology, and tourism, with its capital in Nanjing. Jiangsu is the third smallest, but the fifth most populous and the most densely populated of the 23 provinces of the People's Republic of China. Jiangsu has the highest GDP per capita and second-highest GDP of Chinese provinces, after Guangdong. Jiangsu borders Shandong in the north, Anhui to the west, and Zhejiang and Shanghai to the south. Jiangsu has a coastline of over 1,000 kilometers (620 mi) along the Yellow Sea, and the Yangtze River passes through the southern part of the province.