The Yaquina Bay Bridge is an arch bridge that spans Yaquina Bay south of Newport, Oregon. It is one of the most recognizable of the U.S. Route 101 bridges designed by Conde McCullough and one of eleven major bridges on the Oregon Coast Highway designed by him. It superseded the last ferry crossing on the highway.

Yaquina Bay is a coastal estuarine community found in Newport, Oregon. Yaquina Bay is a semi-enclosed body of water, approximately 8 km2 (3.2 mi2) in area, with free connection to the Pacific Ocean, but also diluted with freshwater from the Yaquina River land drainage. The Bay is traversed by the Yaquina Bay Bridge.