Yitzhak of Volozhin was a rosh yeshiva of the Volozhin Yeshiva.

Yeshivas Etz Ḥayyim, commonly called the Volozhin Yeshiva, was a prestigious Lithuanian yeshiva located in the town of Volozhin, Russian Empire. It was founded around 1803 by Rabbi Ḥayyim Volozhiner, a student of the famed Vilna Gaon, and trained several generations of scholars, rabbis, and leaders. It is considered the first modern yeshiva, and served as a model for later Misnagedic educational institutions.