z/OS is a 64-bit operating system for IBM z/Architecture mainframes, introduced by IBM in October 2000. It derives from and is the successor to OS/390, which in turn was preceded by a string of MVS versions. Like OS/390, z/OS combines a number of formerly separate, related products, some of which are still optional. z/OS has the attributes of modern operating systems but also retains much of the older functionality that originated in the 1960s and is still in regular use—z/OS is designed for backward compatibility.

In computer architecture, 64-bit integers, memory addresses, or other data units are those that are 64 bits wide. Also, 64-bit central processing units (CPU) and arithmetic logic units (ALU) are those that are based on processor registers, address buses, or data buses of that size. A computer that uses such a processor is a 64-bit computer.