Zeynab Begum was the fourth daughter of Safavid king (shah) Tahmasp I, is considered to be one of the most influential and powerful princesses of the Safavid era. She lived during the reigns of five successive Safavid monarchs, and apart from holding diverse functions, including at the top of the empire's bureaucratic system, she was also the leading matriarch in the royal harem for many years, and acted on occasion as kingmaker. She reached the apex of her influence during the reign of King Safi. In numerous contemporaneous sources, she was praised as a "mainstay of political moderation and wisdom in Safavid court politics". She was eventually removed from power by Safi in 1632.

Ali-Qoli Khan Shamlu was a Safavid officer of Turkoman origin. He is mostly remembered for leading a rebellious coalition against then-incumbent kings (shahs) Ismail II and Mohammad Khodabanda. This rebellion guaranteed the survival of the young prince Abbas, for whom he was guardian (laleh).