Zincirlikuyu is a quarter of the Şişli district on the European side of Istanbul, Turkey. Part of Esentepe neighborhood, it is situated on a hilltop on the district border to Beşiktaş in the east. Having undergone redevelopment in recent years, the area is also a busy bus hub.

The Metrobus is a 52 km (32.3 mi) bus rapid transit route in Istanbul, Turkey. The system has 44 stations that follow the city's ring road via Avcılar, Zincirlikuyu and the Bosphorus Bridge to Söğütlüçeşme using dedicated bus lanes for almost the entire length of the route.