The Great Steamboat Race is an annual steamboat race, taking place the Wednesday before the first Saturday of May, three days before the Kentucky Derby, as part of the Kentucky Derby Festival. The race was first run in 1963 and it takes place on the Ohio River in the span that runs between Louisville, Kentucky and Jeffersonville, Indiana. Until 2009, the race was traditionally between the Belle of Louisville and the Delta Queen, although other steamboats have participated. Since 2009, the Delta Queen has not participated due to ownership and legal issues, and the Belle of Cincinnati has taken its place in the competition. In 2012, the Belle of Louisville and Belle of Cincinnati were joined in the race by the American Queen.

Jeffersonville is a city and the county seat of Clark County, Indiana, United States, situated along the Ohio River. Locally, the city is often referred to by the abbreviated name Jeff. It lies directly across the Ohio River to the north of Louisville, Kentucky, along I-65. The population was 49,447 at the 2020 census.