The Richmond–San Rafael Bridge is the northernmost of the east–west crossings of California's San Francisco Bay, carrying Interstate 580 from Richmond on the east to San Rafael on the west. It opened in 1956, replacing ferry service by the Richmond–San Rafael Ferry Company, and was officially renamed in 1981 to honor California State Senator John F. McCarthy, who championed the bridge's creation.

Interstate 580 (I-580) is an approximately 76-mile-long (122 km) east–west auxiliary Interstate Highway in Northern California. The heavily traveled spur route of I-80 runs from US Route 101 (US 101) in San Rafael in the San Francisco Bay Area to I-5 at a point outside the southern city limits of Tracy in the Central Valley. I-580 forms a concurrency with I-80 between Albany and Oakland, the latter of which is the location of the MacArthur Maze interchange immediately east of the San Francisco–Oakland Bay Bridge. I-580 provides a connection from the Bay Area to the southern San Joaquin Valley and Southern California via I-5, as I-5 bypasses the Bay Area to the east.