The St. Francois Mountains in southeast Missouri are a mountain range of Precambrian igneous mountains rising over the Ozark Plateau. This range is one of the oldest exposures of igneous rock in North America. The name of the range is spelled out as Saint Francois Mountains in official GNIS sources, but it is sometimes misspelled in use as St. Francis Mountains to match the anglicized pronunciation of both the range and St. Francois County.

Missouri is a landlocked state in the Midwestern region of the United States. Ranking 21st in land area, it borders Iowa to the north, Illinois, Kentucky and Tennessee to the east, Arkansas to the south and Oklahoma, Kansas, and Nebraska to the west. In the south are the Ozarks, a forested highland, providing timber, minerals, and recreation. The Missouri River, after which the state is named, flows through the center and into the Mississippi River, which makes up the eastern border. With over six million residents, it is the 18th-most populous state of the country. The largest urban areas are St. Louis, Kansas City, Springfield, and Columbia; the capital is Jefferson City.