In the papal conclave held on 29 and 30 December 1370, after the death of Pope Urban V, Cardinal Pierre Roger de Beaufort was elected pope under the name Gregory XI. He thus became seventh and the last pope of the period of Avignon Papacy.

Guy of Boulogne was a statesman and cardinal who served the Avignon Papacy for 33 years. He participated in the papal conclaves of 1352, 1362 and 1370, and was the Subdean of the Sacred College of Cardinals. His diplomatic postings were extensive, including Hungary, Italy, and Spain. He headed an effort to end the Hundred Years' War. The historian Kenneth Setton called him "one of the commanding figures of his day, and the letters of Petrarch abound with references to him".