The 1811 German Coast uprising was a revolt of slaves in parts of the Territory of Orleans on January 8–10, 1811. The uprising occurred on the east bank of the Mississippi River in what is now St. John the Baptist, St. Charles and Jefferson Parishes, Louisiana. The slave insurgency was the largest in U.S. history, but the rebels killed only two White men. Confrontations with militia, combined with post-trial executions, resulted in the deaths of 95 enslaved people.

A slave rebellion is an armed uprising by slaves, as a way of fighting for their freedom. Rebellions of slaves have occurred in nearly all societies that practice slavery or have practiced slavery in the past. A desire for freedom and the dream of successful rebellion is often the greatest object of song, art, and culture amongst the enslaved population. These events, however, are often violently opposed and suppressed by slaveholders.