The 1861 Sumatra earthquake occurred on 16 February and was the last in a sequences of earthquakes that ruptured adjacent parts of the Sumatran segment of the Sunda megathrust. It caused a devastating tsunami which led to several thousand fatalities. The earthquake was felt as far away as the Malay peninsula and the eastern part of Java. The rupture area for the 2005 Nias–Simeulue earthquake is similar to that estimated for the 1861 event.

The Sunda megathrust is a fault that extends approximately 5,500 km (3300 mi) from Myanmar (Burma) in the north, running along the southwestern side of Sumatra, to the south of Java and Bali before terminating near Australia. It is a megathrust, located at a convergent plate boundary where it forms the interface between the overriding Eurasian plate and the subducting Indo-Australian plate. It is one of the most seismogenic structures on Earth, being responsible for many great and giant earthquakes, including the 2004 Indian Ocean earthquake and tsunami that killed over 227,000 people. The Sunda megathrust can be divided into the Andaman Megathrust, Sumatra(n) Megathrust and Java(n) Megathrust. The Bali-Sumbawa segment is much less active and therefore does not have the "megathrust" term associated with it.