The Sunda megathrust is a fault that extends approximately 5,500 km (3300 mi) from Myanmar (Burma) in the north, running along the southwestern side of Sumatra, to the south of Java and Bali before terminating near Australia. It is a megathrust, located at a convergent plate boundary where it forms the interface between the overriding Eurasian plate and the subducting Indo-Australian plate. It is one of the most seismogenic structures on Earth, being responsible for many great and giant earthquakes, including the 2004 Indian Ocean earthquake and tsunami that killed over 227,000 people. The Sunda megathrust can be divided into the Andaman Megathrust, Sumatra(n) Megathrust and Java(n) Megathrust. The Bali-Sumbawa segment is much less active and therefore does not have the "megathrust" term associated with it.

The 2005 Nias–Simeulue earthquake occurred on 28 March off the west coast of northern Sumatra, Indonesia. At least 915 people were killed, mostly on the island of Nias. The event caused panic in the region, which had already been devastated by the massive tsunami triggered by the 2004 Indian Ocean earthquake, but this earthquake generated a relatively small tsunami that caused limited damage. It was the third most powerful earthquake since 1965 in Indonesia.