The 1872 Owens Valley earthquake – also known as the Lone Pine earthquake – struck on March 26 at 02:30 local time in the Owens Valley, with the epicenter near the town of Lone Pine. Its magnitude has been estimated at Mw 7.4 to 7.9, with a maximum Mercalli Intensity of X (Extreme). It was one of the largest earthquakes to hit California in recorded history and was similar in size to the 1906 San Francisco earthquake. Twenty-seven people were killed and fifty-six were injured.

Owens Valley is an arid valley of the Owens River in eastern California in the United States. It is located to the east of the Sierra Nevada, west of the White Mountains and Inyo Mountains, and is split between the Great Basin Desert and the Mojave Desert. The mountain peaks on the West side reach above 14,000 feet (4,300 m) in elevation, while the floor of the Owens Valley is about 4,000 feet (1,200 m), making the valley the deepest in the United States. The Sierra Nevada casts the valley in a rain shadow, which makes Owens Valley "the Land of Little Rain". The bed of Owens Lake, now a predominantly dry endorheic alkali flat, sits on the southern end of the valley.