The 1888 United States presidential election in Alabama was held on November 6, 1888, as part of the concurrent Presidential election in which all thirty-eight contemporary states participated. Alabama voters chose ten electors, or representatives to the Electoral College, who voted for President and Vice-President.

The 1888 United States presidential election was the 26th quadrennial presidential election, held on Tuesday, November 6, 1888. Republican nominee Benjamin Harrison, a former U.S. senator from Indiana, defeated incumbent Democratic President Grover Cleveland of New York. It was the third of five U.S. presidential elections in which the winner did not win the national popular vote, which would not occur again until the 2000 US presidential election.