The 1908 college football season ran from Saturday, September 19, to November 28. The Penn Quakers and the Harvard Crimson each finished the season unbeaten but with one tied. The LSU Tigers went unbeaten and untied against a weaker opposition. All three teams were named national champions retroactively by various organizations. Only Pennsylvania officially claims a national championship for the 1908 season.

The South Dakota State Jackrabbits football program represents South Dakota State University in American football. This article covers the history of the program in the first two decades. Prior to 1904, the school was known as the South Dakota Agricultural College. In 1904, the school was renamed South Dakota State College of Agriculture and Mechanic Arts. The team played its home games at Brookings, South Dakota.