The 1915 Vanderbilt Commodores football team represented Vanderbilt University during the 1915 Southern Intercollegiate Athletic Association football season. Dan McGugin served his 12th season as the Commodores' head coach. Vanderbilt was a member of the SIAA. They faced a 10-game schedule. Vanderbilt scored 459 points in its first seven shutout games, and 514 points in 510 minutes of actual playing time by season's end, making it a legitimate "point-a-minute team" leading the nation in scoring with a school record still unequaled today.

Daniel Earle McGugin was an American college football player and coach, as well as a lawyer. He served as the head football coach at Vanderbilt University in Nashville, Tennessee from 1904 to 1917 and again from 1919 to 1934, compiling a record of 197–55–19. He is the winningest head coach in the history of the university. McGugin was inducted into the College Football Hall of Fame as a coach in 1951 as part of its inaugural class. He was the brother-in-law of University of Michigan coach Fielding H. Yost.