The 2012 NASCAR Camping World Truck Series was the eighteenth season of the third highest stock car racing in the United States. The season was contested over twenty-two races, beginning with the NextEra Energy Resources 250 at Daytona International Speedway and ending with the Ford EcoBoost 200 at Homestead-Miami Speedway. NASCAR announced some changes, including the removal of New Hampshire Motor Speedway, Nashville Superspeedway, and Lucas Oil Raceway from the schedule, and moving the Phoenix race back to its traditional fall date. In addition, Rockingham Speedway was added to the schedule, the first time NASCAR has raced at Rockingham since 2004. James Buescher of Turner Motorsports claimed his first championship with a 13th-place finish in the season finale. Chevrolet won the Manufacturer's Championship with 166 points and 12 wins.

The Fresh From Florida 250 is the first race of the NASCAR Craftsman Truck Series season at Daytona International Speedway and as of 2004 has been held under the lights. It is the Truck Series event of Speedweeks – the series of races leading up to the Daytona 500.