The 2015 NCAA Division I women's basketball tournament was played between March and April 2015, with the Final Four played April 5 & 7. The regional locations, after a one-year experiment allowing tournament teams to host, returned to four neutral sites: Oklahoma City, Spokane, Greensboro and Albany. The subregionals were played 20–23 March, while the regionals were played 27–30 March. This represented a change; in the past, the rounds were played starting on a Saturday and ending on a Tuesday. In 2015, the opening rounds and regionals were played starting on a Friday and ending on a Monday. The Final Four was played at Amalie Arena in Tampa, Florida. For only the third time in history, all four of the number one seeds made it to the Final Four.

Desert Financial Arena is a 14,198-seat multi-purpose arena located at 600 E Veterans Way in Tempe, Arizona, a suburb of Phoenix. It sits immediately east of Mountain America Stadium on the northern edge of the Tempe campus of Arizona State University (ASU).