The 2016 NCAA Division I men's basketball tournament involved 68 teams playing in a single-elimination tournament to determine the men's National Collegiate Athletic Association (NCAA) Division I college basketball national champion for the 2015–16 season. The 78th edition of the Tournament began on March 15, 2016, and concluded with the championship game on April 4 at NRG Stadium in Houston, Texas. This was the first NCAA tournament to adopt the NCAA March Madness branding, including fully-branded courts at each of the tournament venues.

The 2016 NCAA Division I men's basketball championship game was the final game of the 2016 NCAA Division I men's basketball tournament and determined the national champion for the 2015–16 NCAA Division I men's basketball season. The game was played on Monday, April 4, 2016, at NRG Stadium in Houston, Texas, between the Villanova Wildcats and the North Carolina Tar Heels.