The 2016 United States presidential election in Indiana was held on Tuesday, November 8, 2016, as part of the 2016 United States presidential election in which all 50 states plus the District of Columbia participated. Indiana voters chose electors to represent them in the Electoral College via a popular vote, pitting the Republican Party's nominee, businessman Donald Trump, and running mate Indiana Governor Mike Pence against Democratic Party nominee, former Secretary of State Hillary Clinton, and her running mate Virginia Senator Tim Kaine. Indiana has 11 electoral votes in the Electoral College.

Vanderburgh County is a county in the U.S. state of Indiana. As of 2020, the population was 180,136. The county seat is in Evansville. While Vanderburgh County was the eighth-largest county in 2020 population in Indiana, it is also the eighth-smallest county in area and the smallest in southwestern Indiana, covering only 236 square miles (610 km2).