The 2016 United States presidential election in Kentucky was held on Tuesday, November 8, 2016, as part of the 2016 United States presidential election in which all 50 states plus the District of Columbia participated. Kentucky voters chose electors to represent them in the Electoral College via a popular vote, pitting the Republican Party's nominee, businessman Donald Trump, and running mate Indiana Governor Mike Pence against Democratic Party nominee, former Secretary of State Hillary Clinton, and her running mate Virginia Senator Tim Kaine. Kentucky has eight electoral votes in the Electoral College.

Jefferson County is located in the north central portion of the U.S. state of Kentucky. As of the 2020 census, the population was 782,969. It is the most populous county in the commonwealth.