The 2018 United States Senate election in Minnesota took place on November 6, 2018, to elect a United States Senator from Minnesota. Incumbent Democratic–Farmer–Labor U.S. Senator Amy Klobuchar was reelected in a landslide, defeating Republican state House of Representatives member Jim Newberger. This election was held alongside a special election for Minnesota's other Senate seat, which was held by Al Franken until he resigned in January 2018. U.S. House elections, a gubernatorial election, State House elections, and other elections were also held.

The Minnesota Democratic–Farmer–Labor Party (DFL) is a political party in the U.S. state of Minnesota. It is affiliated with the national Democratic Party. The DFL controls four of Minnesota's eight U.S. House seats, both of its U.S. Senate seats, the Minnesota House of Representatives and Senate, and all other statewide offices, including the governorship, making it the dominant party in the state. Its main political rival has been the Republican Party of Minnesota.