The 321st Air Expeditionary Wing was a United States Air Force unit assigned United States Air Forces Central, the USAF component command of United States Central Command. The unit was reestablished on 1 November 2008 and was a nexus of all Coalition Air Force Training Teams and the Iraqi Air Force at COB Speicher. It was previously the 321st Bombardment Group (Medium), which flew B-25 Mitchells in combat with the Northwest African Strategic Air Force in 1943 and the Mediterranean Allied Tactical Air Force in 1944–45.

The North American B-25 Mitchell is an American medium bomber that was introduced in 1941 and named in honor of Brigadier General William "Billy" Mitchell, a pioneer of U.S. military aviation. Used by many Allied air forces, the B-25 served in every theater of World War II, and after the war ended, many remained in service, operating across four decades. Produced in numerous variants, nearly 10,000 B-25s were built, It was the most-produced American medium bomber and the third most-produced American bomber overall. These included several limited models such as the F-10 reconnaissance aircraft, the AT-24 crew trainers, and the United States Marine Corps' PBJ-1 patrol bomber.