The A68 is a major road in the United Kingdom, running from Darlington in England to the A720 in Edinburgh, the capital of Scotland. It crosses the Anglo-Scottish border at Carter Bar and is the only road to do so for some distance either way; the next major crossings are the A697 from Coldstream to Cornhill-on-Tweed in the east, and the A7 near Canonbie to the west.

The Edinburgh City Bypass, designated as A720, is one of the most important trunk roads in Scotland. Circling around the south of Edinburgh, as the equivalent of a ring road for the coastal city, it links together the A1 towards north-east England, the A702 towards north-west England, the M8 through the Central Belt towards Glasgow, the A7 through south-east Scotland and north-west England as well as the A8 leading to the M9 for Stirling and the Queensferry Crossing.