The AP2 adaptor complex is a multimeric protein that works on the cell membrane to internalize cargo in clathrin-mediated endocytosis. It is a stable complex of four adaptins which give rise to a stru
AP2 Adaptor Complex Cryo-EM Structure. Red - alpha subunits. Blue - beta subunit. Green - mu subunit. Yellow - sigma subunit.
Endocytosis is a cellular process in which substances are brought into the cell. The material to be internalized is surrounded by an area of cell membrane, which then buds off inside the cell to form
AP2 adaptor complex
…The AP2 adaptor complex is a multimeric protein that works on the cell membrane to internalize cargo in clathrin-mediated endocytosis. It is a stable complex of four adaptins which give rise to a structure that has a core domain and two appendage domains attached to the core domain…
Schematic drawing illustrating clathrin-mediated (left) and clathrin-independent endocytosis (right) of synaptic vesicle membranes
From left to right: Phagocytosis, Pinocytosis, Receptor-mediated endocytosis.