Agriculture in Mesoamerica dates to the Archaic period of Mesoamerican chronology. At the beginning of the Archaic period, the Early Hunters of the late Pleistocene era led nomadic lifestyles, relying on hunting and gathering for sustenance. However, the nomadic lifestyle that dominated the late Pleistocene and the early Archaic slowly transitioned into a more sedentary lifestyle as the hunter gatherer micro-bands in the region began to cultivate wild plants. The cultivation of these plants provided security to the Mesoamericans, allowing them to increase surplus of "starvation foods" near seasonal camps; this surplus could be utilized when hunting was bad, during times of drought, and when resources were low. The cultivation of plants could have been started purposefully, or by accident. The former could have been done by bringing a wild plant closer to a camp site, or to a frequented area, so it was easier access and collect. The latter could have happened as certain plant seeds were eaten and not fully digested, causing these plants to grow wherever human habitation would take them.

In the classification of the archaeological cultures of North America, the Archaic period in North America, taken to last from around 8000 to 1000 BC in the sequence of North American pre-Columbian cultural stages, is a period defined by the archaic stage of cultural development. The Archaic stage is characterized by subsistence economies supported through the exploitation of nuts, seeds, and shellfish. As its ending is defined by the adoption of sedentary farming, this date can vary significantly across the Americas.