Al-ʻUzzā was one of the three chief goddesses of Arabian religion in pre-Islamic times and she was worshipped by the pre-Islamic Arabs along with al-Lāt and Manāt. A stone cube at Nakhla was held sacred as part of her cult. She is mentioned in Qur'an 53:19 as being one of the goddesses who people worshipped.

A goddess is a female deity. In many known cultures, goddesses are often linked with literal or metaphorical pregnancy or imagined feminine roles associated with how women and girls are perceived or expected to behave. This includes themes of spinning, weaving, beauty, love, sexuality, motherhood, domesticity, creativity, and fertility. Many major goddesses are also associated with magic, war, strategy, hunting, farming, wisdom, fate, earth, sky, power, laws, justice, and more. Some themes, such as discord or disease, which are considered negative within their cultural contexts also are found associated with some goddesses. There are as many differently described and understood goddesses as there are male, shapeshifting, or neuter gods.