Alabama's 6th congressional district is a United States congressional district in Alabama that elects a representative to the United States House of Representatives. It is composed of the wealthier portions of Birmingham, nearly all of Jefferson County outside Birmingham, most of Blount County, and the entirety of Bibb, Chilton, Coosa, and Shelby counties.

Jefferson County is the most populous county in the U.S. state of Alabama, located in the central portion of the state. As of the 2020 census, its population was 674,721. Its county seat is Birmingham. Its rapid growth as an industrial city in the 20th century, based on heavy manufacturing in steel and iron, established its dominance. Jefferson County is the central county of the Birmingham-Hoover, AL Metropolitan Statistical Area.