Alaska Airlines Flight 261 was an Alaska Airlines flight of a McDonnell Douglas MD-80 series aircraft that crashed into the Pacific Ocean on January 31, 2000, roughly 2.7 miles north of Anacapa Island, California, following a catastrophic loss of pitch control, killing all 88 on board: two pilots, three flight attendants, and 83 passengers. The flight was a scheduled international passenger flight from Licenciado Gustavo Díaz Ordaz International Airport in Puerto Vallarta, Jalisco, Mexico, to Seattle–Tacoma International Airport near Seattle, Washington, United States, with an intermediate stop at San Francisco International Airport near San Francisco, California.

Anacapa Island is a small volcanic island located about 11 miles off Port Hueneme in Ventura County, California. The island is composed of a series of narrow islets 6 mi (10 km) long, oriented generally east–west and 5 mi (8 km) east of Santa Cruz Island. The three main islets, East, Middle and West Anacapa, have precipitous cliffs, dropping off steeply into the sea.