Alejandro Encinas Rodríguez is a Mexican left-wing politician who served as the acting Secretary of the Interior in June 2023. He was previously affiliated with the Party of the Democratic Revolution, the Unified Socialist Party of Mexico, the Mexican Socialist Party and the Mexican Communist Party. He served as the 4th Head of Government of the Federal District from 2005 to 2006. Encinas serves in the upper house of Congress as senator representing the State of Mexico.

The Mexican Secretariat for Home Affairs is the public department concerned with the country's domestic affairs, the presenting of the president's bills to Congress, their publication on the Official Journal of the Federation, and certain issues of national security. The country's principal intelligence agency, CISEN, is directly answerable to the Secretary of the Interior. The Secretary is a member of the President's Cabinet and is, given the constitutional implications of the post, the most important Cabinet Member. Additionally, in case of absolute absence of the President, the Secretary of Interior assumes the executive powers of the President provisionally. The Office is practically equivalent to Ministries of the Interior in most other countries and is occasionally translated to English as Ministry, Secretariat or Department of the Interior.