Amatrice is a town and comune in the province of Rieti, in northern Lazio, and the center of the food-agricultural area of Gran Sasso e Monti della Laga National Park. The town was devastated by a powerful earthquake on 24 August 2016. It is one of I Borghi più belli d'Italia.

Central Italy is one of the five official statistical regions of Italy used by the National Institute of Statistics (ISTAT), a first-level NUTS region, and a European Parliament constituency.